Effect of enteral nutrition support on patients with edematous pancreatitis

Xiong Huanhong; Chen Qiming; Zhu Siqi; Huang Lei

doi:10.3760/cma.j.issn.1673-4777.2017.08.020

Abstract：Objective To explore the effect of enteral nutrition support on prognosis of edematous pancreatitis.Methods Totally 100 patients with edematous pancreatitis were enrolled from June 2015 to June 2016 in Peking University Shenzhen Hospital;patients who were admitted from June to December 2015 had parenteral nutrition support based on fasting,gastrointestinal decompression and anti-infection therapy (control group);patients who were admitted from December 2015 to June 2016 had enteral nutrition support based on basic therapies(observation group).After 2 weeks of treatment,scores of Sepsis-related Organ Failure Assessment(SOFA),Acute Physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ) and modified Marshall Scale were evaluated;levels of blood glucose and urine amylase,incidence of adverse reactions,recovery time of main symptoms and length of hospital stay were recorded.Results After treatment,scores of APACHE Ⅱ and modified Marshall Scale,levels of blood glucose and urine amylase,incidences of secondary infection and complications in observation group were significantly lower than those in control group [(7.3 ± 1.7) points vs (10.0 ± 1.7) points,(0.8 ± 0.6) points vs (1.2 ± 0.7) points,(6.33 ± 0.16) mmoL/L vs (6.58 ± 0.11) mmol/L,(327 ± 218) U/L vs (544 ± 340)U/L,16.7％ (8/48) vs 38.5％ (20/52),25.0％ (12/48) vs 42.3％ (22/52)] (P ＜ 0.05);systemic inflammatory response syndrome improving time,temperature recovery time,abdominal distension and pain duration time and hospital stay time in observation group were significantly shorter than those in control group [(2.61±0.24)dvs (5.49±1.31)d,(6.6±1.3)dvs (10.2±3.3)d,(2.7±1.0)dvs (5.1 ±1.2)d,(19± 7) d vs (32 ± 7) d] (P ＜ 0.05).Conclusion Enteral nutrition support can effectively relieve illness,reduce complications and promote recovery in patients with edematous pancreatitis.