Effect of cerebral collateral circulation on early neurological function in patients with acute cerebral infarction
Ren Bo
Mao Wenjing
Liu Bin
Zhao Bin
Zhang Jinxia
Li Shiying
Deng Chunying
Zhang Wenyan
Ma Yuanyuan
Wang Yichao
Abstract：Objective To investigate the effect of collateral circulation on early neurological function in patients with acute cerebral infarction.Methods Totally 225 patients with acute cerebral infarction in North China University of Science and Technology Affiliated Hospital were enrolled from January 2015 to June 2016.Anterior and posterior circulation lesions were diagnosed by CT or magnetic resonance imaging examination;cerebral collateral circulation was evaluated by 256 slice spiral CT angiography.The degree of neurological deficits was evaluated by the National Institute of Health Stroke Scale(NIHSS) and Activities of Daily Living(ADL) before and 14 d after hospitalization.Results There were 128 cases (56.9％) of anterior circulation lesion (group A) and 97 cases(43.1％) of posterior circulation lesion (group B).Group A had 77 cases (60.2％) of collateral circulation;group B had 38 cases (39.2％) of collateral circulation;the collateral circulation rate in group A was significantly higher than that in group B (P =0.002).In 225 cases,NIHSS and ADL scores had no significant differences between patients with and without collateral circulation (P ＞ 0.05).In group A and group B,the NIHSS score [(3.6 ± 2.3) points vs (5.0 ± 2.6) points,(3.7 ± 2.4) points vs (5.0 ± 3.4) points] and ADL score after 14 d of hospitalization in patients with collateral circulation were significantly lower than those in patients without collateral circulation(P ＜ 0.05).Conclusion Collateral circulation is beneficial to early recovery of neurological function in patients with acute cerebral infarction,especially in anterior circulation infarction.
Keywords：Cerebral infarctionCollateral circulationCT angiographyNational Institute of Health Stroke ScaleActivities of Daily Living
Publication Date：2017-08-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1172-1175 )