A case of interstitial lung disease complicated with respiratory failure related to rituximab injection
Yang Yong
Luo Chenjing
Yang Yang
Abstract：Objective To investigate the association between interstitial lung disease(ILD) and the use of rituximab injection in patients with immune thrombocytopenia(ITP);to analyze characteristics,pathogenesis and therapeutic measures of rituximab-induced ILD.Methods One case of ILD after treatment with rituximab injection for ITP was analyzed.Results The patient was a young women who was intravenously administered rituximab injection 600 mg once and had small dose of glucocorticoid therapy for 2 months before the occurrence of ILD.The patient had broad-spectrum antibacterial agents and high-dose corticosteroid therapy after admission at Sichuan Provincial People's Hospital and finally died of respiratory failure.The patient had no other ILD risk factors;the occurrence of ILD might be associated with rituximab injection.Conclusion Rituximab-induced ILD is rare and insidious with diverse clinical manifestations.
Keywords：Interstitial lung diseaseRituximabImmune thrombocytopenia
Publication Date：2017-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1161-1163 )