Risk factors of early postoperative mortality in total anomalous pulmonary venous connection
Chen Yan
Liu Yinglong
Su Junwu
Cheng Pei
Zhang Jing
He Yan
Abstract：Objective To analyze risk factors of early postoperative mortality in total anomalous pulmonary venous connection (TAPVC).Methods Totally 187 children who underwent one-stage radical operation for TAPVC in Beijing Anzhen Hospital,Capital Medical University were respectively enrolled from January 2011 to December 2015.Eleven children died in 30 d after operation.Operation related indexes were analyzed between death group(11 cases) and survival group(176 cases).Risk factors of early postoperative mortality were analyzed by logistic regression analysis.Results The early mortality rate was 5.9％ (11/187),including 4 cases of mixed TAPVC;low cardiac output (6 cases) was the main complication in death group.There were statistical significances regarding diagnostic type (P =0.024),preoperative blood oxygen saturation (P =0.020),left ventricular end-diastolic diameter (P =0.024),pulmonary vein velocity (P =0.046),pulmonary artery pressure (P =0.010),ascending aorta blocking time (P ＜ 0.001),intraoperative cardiopulmonary bypass (CPB) time (P ＜ 0.001),postoperative left ejection fraction (P =0.003),left ventricular end-diastolic diameter (P =0.010),pulmonary vein maximum velocity(P =0.010),positive inotropic drug score (P ＜ 0.001) and left atrial pressure (P =0.001) between groups.Backward logistic regression analysis suggested that CPB time(odds ratio =1.017,P =0.049) and positive inotropic drug score (odds ratio =1.119,P =0.032) were independent risk factors of early mortality after operation.Conclusion CPB time and positive inotropic drugs score are independent risk factors of postoperative early mortality of TAPVC.
Keywords：Total anomalous pulmonary venous connectionRisk factors
Publication Date：2017-08-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1149-1152 )