Clinical features of Takayasu's arteritis complicated with coronary artery lesions
Xu Guanyi
Liu Wenxian
Yang Kun
Zhu Jiajia
Ren Yanlong
Abstract：Objective To analyze clinical features of Takayasu's arteritis(TA) patients complicated with coronary artery lesions.Methods Four hundreds and seventy-four TA patients who were admitted in Beijing Anzhen Hospital,Capital Medical University from July 2003 to June 2015 were retrospectively analyzed;62 patients with coronary artery involvement were selected as observation group.One hundred and twenty-four patients with coronary atherosclerotic heart disease were selected as control group.Clinical data,erythrocyte sedimentation tate (ESR),C-reactive protein (CRP) and features of coronary artery lesions were analyzed.Results There were more female patients in observation group;there were less patients with hyperlipemia history,diabetes history,smoking and more patients with ESR ＞20 mrn/1 h and CRP ＞ 15 mg/L than those in control group[67.7％ (42/62) vs 23.6％ (28/124),17.7％ (11/62) vs 41.9％ (52/124),3.2％ (2/62) vs 26.6％ (33/124),4.8％ (3/62) vs 41.1％ (51/124),35.5％ (22/62) vs 3.2％ (4/124),46.7％ (29/62) vs 16.9％ (21/124)];the differences were significant (P ＜ 0.05).Cardiovascular symptoms had no significant differences between groups (P ＞ 0.05).Headache and pain of limbs [66.1％ (41/62)],hypodynamia [58.1％ (36/62)] and hypertension[56.1％ (35/62)] were common symptoms in patients with TA involving coronary artery.Left main coronary and coronary ostium involving rates in observation group were significantly higher than those in control group[8.5％ (12/142) vs 3.3％ (6/180),40.1％ (57/142) vs 7.2％ (13/180)] (P ＜ 0.01);proximal coronary artery and middle coronary artery involving rates in observation group were significantly lower than those in control group[18.3％ (26/142) vs 32.8％ (59/180),21.1％ (30/142) vs 35.6％ (64/180)] (P ＜ 0.05).Conclusion Takayasu arteritis complicated with coronary artery lesions is more common in female,left main coronary artery and coronary ostium.
Keywords：Takayasu's arteritisCoronary arteryCoronary atherosclerotic heart disease
Publication Date：2017-08-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1129-1132 )