Relevance between small intestinal bacterial overgrowth and complications of severe acute pancreatitis
Zhu Hongming
Zhang Mei
Li Bangyi
Zhao Dandan
Zheng Longzhang
Abstract：Objective To investigate the relevance between small intestinal bacterial overgrowth (SIBO) and complications of severe acute pancreatitis(SAP).Methods From January 2014 to June 2016,92 patients with SAP and 91 patients with moderate acute pancreatitis(MAP) in Xuanwu Hospital,Capital Medical University had hydrogen breath test in 48 h after admission to determine SIBO.Complications including infection,local complications,organ failure and systemic inflammatory response syndrome (SIRS) were recorded.Results The positive rate of SIBO was 26.1％ (24/92) in SAP group and 8.8％ (8/91) in MAP group,the difference was statistically significant between groups (P ＜ 0.05).Logistic regression analysis showed that organ failure and SIRS were correlated with SIBO (correlated coefficient =2.092,0.068;P ＜ 0.05).Conclusion SIBO is correlated with complications of organ failure and SIRS in patients with SAP.
Keywords：PancreatitisOrgan failureSystemic inflammatory response syndromeSmall intestinal bacterial overgrowth
Publication Date：2017-06-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 884-887 )