Relation between serum prolidase activity and coronary slow flow
Sun Jingang
Zhang Kai
Wang Zhisheng
Fang Dongping
Abstract：Objective To investigate the relation between serum prolidase activity (SPA) and coronary slow flow(CSF).Methods Eighty patients with chest pain from January to December 2015 in Beijing Anzhen Hospital,Capital Medical University were enrolled.The patients were divided into control group[normal coronary artery(diameters of 3 main arteries and branch vessels ＞2 mm) and normal coronary blood flow] and CSF group (normal coronary artery but at least 1 artery had CSF) according to coronary angiography,with 40 cases in each group.CSF was diagnosed by thrombolysis in myocardial infarction frame count(TFC).SPA was tested by spectrophotometry.Results There were no significant differences of clinical general data between groups (P ＞ 0.05).SPA in CSF group was significantly higher than that in control group [(703 ± 14) U/L vs (684 ± 13) U/L] (P ＜ 0.0l).SPA was positively correlated with mean TFC (r =0.463,P ＜ 0.001).Receiver operator characteristic curve showed that SPA 681.3 U/L had the highest accuracy in diagnosis of CSF,the sensitivity and specificity were 97.5％ and 52.5％ respectively.Conclusion Patients with CSF have a high level of SPA;SPA is positively correlated with mean TFC.
Keywords：Coronary slow flowSerum prolidase activityCollagen
Publication Date：2017-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 508-512 )