Efficacy analysis of drug-eluting balloon in treating coronary atherosclerotic heart disease

doi:10.3760/cma.j.issn.1673-4777.2017.03.002

Abstract：Objective To observe efficacy and safety of drug-eluting balloon in the treatment of coronary atherosclerotic heart disease(CHD).Methods Sixty-four patients with CHD who had drug-eluting balloon therapy from January 2015 to August 2015 in Beijing Anzhen Hospital,Capital Medical University were enrolled as observation group;each patient was matched with 1 case of CHD with same lesion type and similar age who had drug-eluting stents therapy as control group.All patients were followed up for 12 months after operation.Incidence of angina pectoris attack and major adverse cardiac events (MACE) (death,acute myocardial infarction,target lesion revascularization) were recorded at 3,9,12 months after operation.Results Incidences of angina pectoris and MACE had no significant differences between observation and control group at 3,9,12 months after operation [angina pectoris:14.1％ (9/64) vs 21.9％ (14/64),P =0.250;15.6％ (10/64) vs 23.4％ (15/64),P =0.265;15.6％(10/64) vs 26.6％(17/64),P=0.129;MACE:4.7％ (3/64) vs 3.1％ (2/64),P=0.648;7.8％ (5/64) vs 9.4％ (6/64),P =0.752;10.9％ (7/64) vs 12.5％ (8/64),P =0.783].At 3 months after operation,3 patients in observation group discontinued dual-antiplatelet agents and took single antiplatelet agent;1 patient completely stopped antiplatelet agents;those 4 patients had no MACE until 12 months after operation.Conclusion Clinical efficacy and safetv of drug-eluting balloon in the treatment of CHD are optimistic.