Risk analysis of slow reperfusion arrhythmia in acute ST-segment elevation myocardial infarction patients after primary percutaneous coronary intervention
Li Yong
Lyu Shuzheng
Abstract：Objective To investigate risk factors of slow reperfusion arrhythmia in acute ST-elevation myocardial infarction(STEMI) patients after primary percutaneous coronary intervention(PPCI).Methods Totally 332 acute STEMI patients undergoing PPCI from January 2007 to January 2010 in Beijing Anzhen Hospital,Capital Medical University were enrolled.The patients were divided into slow reperfusion arrhythmia group(92 cases) and control group(240 cases) after operation.Clinical items were recorded to analyze risk factors of slow reperfusion arrhythmia.Results The incidence of slow reperfusion arrhythmia was 27.7％ (92/332).Single vessel lesion rate,left anterior descending branch lesion rate,incomplete culprit vessel occlusion rate and level of high density lipoprotein in slow reperfusion arrhythmia group were significantly lower than those in control group [31.5％ (29/92) vs 46.7％ (112/240),25.0％ (23/92) vs 57.1％ (137/240),26.1％ (24/92) vs 38.8％ (93/240),(0.99 ± 0.22) mmol/L vs (1.06 ± 0.28) mmol/L] (P ＜ 0.05).Left circumflex artery lesion rate,right coronary artery lesion rate,intraoperative no-reflow incidence,hypotension incidence and manual thrombus suction device use rate in slow reperfusion arrhythmia group were significantly higher than those in control group [57.6％ (53/92) vs 32.5％ (78/240),17.4％ (16/92) vs 9.6％ (23/240),15.2％ (14/92) vs 6.7％ (16/240),18.5％ (17/92) vs 4.6％ (11/240),81.5％ (75/92) vs 63.3％ (152/240)] (P ＜ 0.05).Multivariate logistic regression analysis showed that left circumflex coronary artery lesion (odd ratio =3.822,95％ confidence interval:2.093-6.977),right coronary artery lesion (odd ratio =3.798,95％ confidence interval:1.609-8.960),intraoperative hypotension(odd ratio =4.719,95％ confidence interval:1.951-11.417),intraoperative no-reflow (odd ratio =2.563,95％ confidence interval:1.130-5.810) and using manual thrombus suction device(odd ratio =2.095,95％ confidence interval:1.099-3.995) were independent risk factors of reperfusion arrhythmia after PPCI.Conclusion Left circumflex coronary artery lesion,right coronary artery lesion,intraoperative hypotension,intraoperative no-reflow and manual thrombus suction device use are independent risk factors of slow reperfusion arrhythmia in acute STEMI patients after PPCI.
Keywords：Coronary artery diseaseArrhythmiaMyocardial infarctionPercutaneous coronary interventionRisk factor
Publication Date：2017-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 321-325 )