Analysis of thyroid function in patients with papillary thyroid carcinoma and nodular goiter
Dong Yong
He Jianye
Hou Yingchen
Li Yang
Abstract：Objective To analyze the thyroid function in patients with papillary thyroid carcinoma (PTC) and nodular goiter(NG).Methods A total of 216 patients with thyroid nodules from August 2011 to July 2013 at Beijing Anzhen Hospital,Capital Medical University were enrolled;115 cases were diagnosed of PTC by postoperative pathology(PTC group);101 cases were diagnosed of nodular goiter(NG group).Gender,age,thyroid stimulating hormone(TSH),total triiodothyronine (TT3),total thyroxine (TT4),free triiodothyronine(FT3),free thyroxine (FT4),thyroglobulin antibody (TGAb) and thyroid microsomal antibody (TMAb) were analyzed.Results The average age of PTC group was significantly lower than that of NG group [(44 ± 13)years vs (50 ± 13)years];the level of TGAb in PTC group was significantly higher than that in NG group [(32 ± 27) mIU/L vs (14 ± 11) mIU/L] (P ＜ 0.05).Gender,TSH,TT3,TT4,FT3,FT4 and TMAb levels had no significant differences between groups (P ＞ 0.05).TGAb level was an independent risk factor of PTC;age was a protective factor of PTC (P ＜ 0.05).Conclusion Levels of TSH and thyroid hormone have no difference between patients with PTC and NG;both PTC and NG are common in female;age and TGAb level can be differentiating indicators for PTC and NG.
Keywords：Papillary thyroid carcinomaNodular goiterThyroid stimulating hormoneThyroid hormone
Publication Date：2017-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 68-71 )