Curative effect of surgical resection combined with transcatheter arterial chemoembolization on primary hepatoma
Lu Lei
Ye Xinping
Abstract：Objective To investigate the curative effect of surgical resection combined with postoperative transcatheter arterial chemoembolization (TACE) on primary hepatoma.Methods Totally 82 cses of Barcelona Clinic Liver Cancer(BCLC) stage A primary hepatoma from April 2008 to March 2010 in the First Affiliated Hospital of Guangxi Medical University were retrospectively analyzed.All patients were divided into observation group(40 cases,treated with surgical resection combined with TACE) and control group(40 cases,treated with surgical resection).Postoperative 1-,3-,5-year survival rates and complications were recorded.Prognostic factors of hepatectomy were analyzed.Results Postoperative 1-,3-,5-year survival rates in observation group were significantly higher than those in control group [90.0％ (36/40) vs 66.7％ (28/42),75.0％ (30/40) vs 40.5％(17/42),52.5％ (21/40) vs 19.0％ (8/42)] (P ＜ 0.05).There was no significant difference of complication incidence between groups(P ＞ 0.05).Preoperative alpha-fetoprotein level,Child-Pugh classification of liver function,tumor numbers,tumor size and postoperative TACE were independent prognostic factors of hepatectomy(P ＜0.05).Conclusion Surgical resection combined with postoperative TACE can significantly improve the survival rate of patients with BCLC-A primary hepatoma.
Keywords：CarcinomahepatocellularTranscatheter arterial chemoembolizationPostoperative survival rate
Publication Date：2016-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1790-1794 )