Effect of acarbose and metformin on body mass reduction: a Meta-analysis
Xu Qinglei
Shen Xue
Dong Jianjun
Wu Xiaoyun
Liu Jiaxin
Liao Lin
Abstract：Objective To evaluate the effect of acarbose and metformin on body mass reduction.Methods Clinical randomized control trials regarding acarbose and metformin reducing body mass were searched in databases of PubMed,Embase,China Biology Medicine (CBM),China National Knowledge Infrastructure (CNKI),China Science and Technology Journal Database(VIP) and Wanfang Data from their inception to January 2016.Clinical data were evaluated.Review Manager 5.2 software was used for statistical analysis.Results Finally 7 literatures with 983 patients were included.Meta-analysis showed that the effect of acarbose on reducing body mass was better than that of metformin(mean difference =-0.94,95％ confidence interval:-1.24 to-0.65,P ＜ 0.000 01).Conclusion Acarbose is superior to metformin in reducing body mass.
Keywords：AcarboseMetforminBody massRandomized controlled trialMeta-analysis
Publication Date：2016-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1489-1492 )