Clinical effect of lumbar pedicle internal fixation combined with intervertebral bone graft fusion in treating lumbar spondylolisthesis

Hu Xuebin; Feng Dajun; Liu Yu; Ye Jinbiao

doi:10.3760/cma.j.issn.1673-4777.2016.09.021

Abstract：Objective To explore the clinical effect of lumbar pedicle internal fixation combined with intervertebral bone graft fusion in treating lumbar spondylolisthesis.Methods Totally 100 patients with lumbar spondylolisthesis from July 2012 to August 2015 were randomly divided into observation group (50 cases) given lumbar pedicle internal fixation combined with intervertebral bone graft fusion and control group (50 cases) given single lumbar pedicle internal fixation.Six months after operation,the reduction rate,fusion rate,visual analogue scale (VAS) score and Oswestry disability index (ODI) were compared between groups,the complications were observed.Results The reduction rate and fusion rate in observation group were significantly higher than those in control group [100.0％ (50/50) vs 94.0％ (47/50),82.0％ (41/50) vs 72.0％ (36/50)] (P ＜ 0.05).Before treatment,VAS score and ODI score were not significantly different between groups (P ＞ 0.05);6 months after operation,the VAS score and ODI score were significantly decreased compared with those before operation in both observation group [(1.2 ± 0.5) scores vs (7.2 ± 1.3) scores,(5.3 ± 1.2) scores vs (33.4 ± 4.8) scores]and control group [(4.1 ± 0.9) scores vs (7.4 ± 1.3) scores,(17.6 ± 2.7) scores vs (32.9 ± 4.7) scores],and they were more lower in observation group (P ＜ 0.05).The incidence of complication in observation group was significantly lower than that in control group [10.0％ (5/50) vs 26.0％ (13/50)] (P ＜ 0.05).Conclusion Lumbar pedicle internal fixation combined with intervertebral bone graft fusion has good effect in treating lumbar spondylolisthesis,with less complications.