Function of cardiac autonomic nerve at interictal phase in patients with epilepsy
Abstract：Objective To assess the function of cardiac autonomic nerve at interictal phase in patients with epilepsy.Methods Seventy-seven epileptic patients (observation group) and 77 healthy volunteers (control group) from January 2013 to January 2015 were enrolled.The potential amplitude of sensory transduction of gastrocnemius nerve,R-R interval variation and heart rate during resting state and deep breath,Valsalva ratio,ratio of R-R interval 30 s and 15 s (R-R30s/R-R15s) after postural change were compared between groups.Results The potential amplitude of sensory transduction of gastrocnemius nerve,R-R interval variation under during resting state and deep breath,Valsalva ratio and R-R30 s/R-R15 s in observation group were all significantly lower than those in control group [(13 ±7) μV vs (17 ±8) μV,(17 ±7)％ vs (19 ±7)％,(32 ± 14)％ vs (37±14)％,(1.4±0.3) vs (1.8 ±0.4),(1.20 ±0.19) vs (1.30±0.18)] (P.＜0.05).The heart rate during resting state and deep breath had no significant difference (P ＞ 0.05).Conclusion The function of cardiac autonomic nerve at interictal phase in patients with epilepsy is reduced and can be screened by simple and routine tests of autonomic nerve.
Keywords：EpilepsyCardiac autonomic nervousHeart rate
Publication Date：2016-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 213-215 )