Comparison of cardio-ankle vascular index between health persons and dyslipidemia patients without diabetes and hypertension
Sang Cheng
Hao Hengjian
Xu Ji
Abstract：Objective To compare the cardio-ankle vascular index (CAVI) between health persons and dyslipidemia patients without diabetes and hypertension.Methods One hundred and sixty-nine dyslipidemia patients (observation group) without diabetes and hypertension from September 2012 to May 2014 were selected and were divided into hypercholesterolemia subgroup (FH subgroup,103 cases) and hyperlipidemia subgroup (CH subgroup,66 cases).In addition,264 healthy volunteers were enrolled (control group).The gender,age,body mass index (BMI),smoking status,total cholesterol (TC),high density lipoprotein-cholesterol (HDL-C),low density lipoprotein-cholesterol (LDL-C),triglyceride (TG),apoli poprotein A(Apo A),Apo B,blood pressure and CAVI were compared among groups.Results The levels of TC,LDL-C,TG,Apo B and diastolic blood pressure in observation group,FH subgroup and CH subgroup were all significantly different with those in control group [6.1 (4.3,10.4),6.4 (4.3,9.6),6.0 (4.7,10.4) mmol/L vs 4.9 (3.2,6.5) mmol/L,4.2 (2.5,6.4),4.3 (2.5,6.1),4.1 (2.6,6.4) mmol/L vs 2.7 (1.4,2.8) mmol/L,1.4 (0.5,7.1),1.2 (0.5,7.0),1.6 (0.5,7.1) mmol/Lvs0.8 (0.3,2.4) mmol/L,1.1 (0.6,1.8),1.3 (0.7,1.8),1.1 (0.6,1.7) g/L vs0.8 (0.8,1.9) g/L,80 (70,101),80 (71,94),80 (73,101) mmHg vs87 (71,103) mmHg] (P＜0.05);the HDL-C and CAVI in observation group and CH subgroup were significantly different with those in control group [1.6 (1.0,2.5),1.8 (1.5,2.5) mmol/L vs 1.4 (1.0,2.2) mmol/L,7.9 (5.6,10.1),8.4 (6.1,10.1) vs7.2 (5.4,10.3)] (P＜0.05);the Apo A in CH subgroup was significantly lower than that in control group [1.5 (1.3,3.2) g/L vs 1.7 (1.2,3.3) g/L] (P ＜ 0.05);the levels of HDL-C,LDL-C and TG in FH subgroup and CH subgroup were significantly different [1.4 (1.0,2.2) mmol/L vs 1.8 (1.5,2.5) mmol/L,4.3 (2.5,6.1) mmol/L vs 4.1 (2.6,6.4) mmol/L,1.2 (0.5,7.0) mmol/Lvs 1.6 (0.5,7.1) mmol/L] (P＜0.05).Pearson linear correlation analysis showed that TC and TG were positively correlated with CAVI in observation group (r =0.283,P =0.026,r =0.383,P ＜ 0.001).Conclusions Compared with that in healthy person,the CAVI were significantly increased in dyslipidemia patients without diabetes and hypertension;there were positively correlations between CAVI and TC,TG.
Keywords：DyslipidemiaDiabetesHypertensionCardio-ankle vascular index
Publication Date：2016-02-28
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 176-180 )