Relationship between lymph node metastases and clinicopathological features of gastric cardia cancer in Chaoshan area
Chen Guangcan
Chen Juntian
Li Wei
Lin Wenting
Guo Dan
Liu Shuhui
Abstract：Objective To observe relationship between lymph node metastases and clinicopathological features of gastric cardia cancer in Chaoshan area.Methods Clinical data from 304 patients with gastric cardia cancer were collected.The age, sex, maximum tumor diameter, gross type, differentiation degree, depth of tumor invasion, and status of surgical margins were recorded and their correlations with the clinicopathological features were analyzed by Logistic regression Analysis.Results In 304 patients, totally 2 844 lymph nodes were retrieved with average number of 9.36/case;the lymph node metastasis ratio was 28.9％ (822/2 844) and metastasis rate was 44.5％ (275/618).The metastasized lymph node included abdominal and thoracic lymph nodes, the metastasis ratio and metastasis rate of abdominal lymph nodes were significantly higher than those of thoracic lymph nodes [29.4％ (807/2 749) vs 15.8％ (15/95), 46.3％ (266/574) vs 20.5％ (9/44)] (P＜0.01).Multiple factors Logistic regression analysis showed that the maximum tumor diameter and differentiation degree were correlated with lymphatic metastasis [OR =2.898, 95％ CI: 1.446-5.807, P =0.003;OR =1.763, 95％ CI: 1.053-2.950, P =0.031].Conclusions Gastric cardia cancer can metastasize to abdominal and thoracic lymph nodes, mainly to abdominal lymph nodes;maximum tumor diameter and tumor differentiation degree are correlated with lymoh node metastases.
Keywords：Gastric cardia cancerLymphatic metastasisMaximum tumor diameterLogistic regression analysis
Publication Date：2016-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 76-79 )