Clinical significance of cardiac magnetic resonance imaging in children with myocarditis
Xu Wenya
Liu Guiying
Su Ying
Yang Xi
Abstract：Objective To evaluate the signification of cardiac magnetic resonance (CMR) imaging in diagnosing myocarditis in children.Methods Totally 50 patients with myocardial damage symptoms who underwent CMR from April 2011 to May 2015 were retrospectively analyzed.According to the clinical diagnosis criteria of myocarditis, the children were divided into myocarditis group (29 cases) and myocardial damage group (21 cases).The imaging features and biochemical data, including cardiac troponin Ⅰ (cTNI) and creatine kinase MB (CK-MB), were compared between groups.Results CMR of myocarditis group showed positive performance, 13 cases accorded with CMR diagnosis criterion of myocarditis and the other 16 cases did not [hyperintense on T2 image was observed in 13 cases (course ＜ 1 month), early phase contrast enhancement signal was observed in 1 case (course ＞ 1 month), delayed contrast enhancement signal was oberved in 2 cases (course ＜ 1 month)].In myocardial damage group, 17 cases showed positive CMR performance, among them 4 cases accorded with CMR diagnosis criterion of myocarditis and the other 17 cases did not [hyperintense on T2 image was observed in 9 cases (course ＜ 1 month 7 cases) , delayed contrast enhancement signal was observed in 2 cases (course ＜ 1 month in 2 cases), no abnormity was found in 4 cases].The hyperintense on T2 image suggested myocardial edema, according with early changes of myocarditis, early phase contrast enhancement suggested capillary leakage or fibrosis of myocardial;delayed contrast enhancement suggested necrosis or fibrosis of myocardial.The rate of positive performance was significantly different between myocarditis group and myocardial damage group [100.0％ (29/29) vs 81.0％ (17/21)] (P ＜ 0.05);the CMR diagnosis rate showed no significant difference between groups [44.8％ (13/29) vs 19.0％ (4/21)] (P ＞ 0.05).In myocarditis group, the CMR diagnosis rate was not significantly different with the positive rate of cTnI and CK-MB (P ＞ 0.05);the positive rate of cTnI was significantly higher than that of CK-MB (P ＜ 0.01).Conclusion CMR can dynamically and visually detect the pathological changes of myocardial tissue, thus is beneficial to assessment of the severity of myocarditis.
Keywords：MyocarditisCardiac magnetic resonance imagingTroponinCreatine kinase isoenzyme
Publication Date：2016-01-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1-5 )