Influence and safety of Tanreqing injection on liver function in virus hepatitis : a Meta-analysis
Tang Qiling
Sun Yongxu
Hu Xiaofan
Lu Congxiao
Abstract：Objective To evaluate the influence and safety of Tanreqing injection on liver function in virus hepatitis using Meta-analysis.Methods China National Knowledge Infrastructure (CNKI), Wanfang database, PubMed and Ovid database were searched to retrieve the relevant studies from 2003 to August of 2014.According to the including and excluding criteria, the literatures were included, then the data were extracted and the study quality was assessed.Meta-analysis was performed by using RevMan 5.3.5 software.Results Eleven randomized controlled trials including 864 patients were included;the patients were all divided into observation group and control group.Meta-analysis showed that compared with those in control group, the liver function indices such as total bilirubin, aspartate aminotransferase and alanine aminotransferase were better improved in observation group compared with those in control group [mean difference (MD) : 15.50, 95％ confidence interval (CI) :13.85-17.15, P＜0.000 01;MD: 20.42, 95％CI: 3.99-36.84, P=0.01;MD: 23.57, 95％CI: 0.80-46.35,P =0.04].Conclusions Tanreqing injection can effectively improve the liver function indices such as total bilirubin, aspartate aminotransferase and alanine aminotransferase;while more clinical trials with higher quality are need to support the conclusion because the included literatures in this study show low quality.
Keywords：Virus hepatitisTanreqing injectionTotal bilirubinAspartate aminotransferaseAlanine aminotransferaseMeta-analysis
Publication Date：2015-12-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1771-1775 )