Effect of continuous positive airway pressure on levels of hemoglobin and high sensitivity C-reactive protein in patients with severe obstructive sleep apnea-hypopnea syndrome
Tang Yongjing
Chen Ying
Abstract：Objective To investigate the effect of continuous positive airway pressure (CPAP) on levels of hemoglobin and high sensitivity C-reactive protein (hs-CRP) in patients with severe obstructive sleep apneahypopnea syndrome (OSAHS).Methods Thirty severe OSAHS patients (observation group) and 27 healthy volunteer (control group) from July 2012 to February 2014 were enrolled.The levels of hemoglobin and hs-CRP were compared between groups.After.6 months of treatment, the levels of hemoglobin and hsoCRP in observe group were reexamined and compared with those before treatment.Results The levels of hemoglobin and hs-CRP in observe group were significantly higher than those in control group before treatment [(146 ± 7) g/L vs (132 ± 8) g/L, (5.0 ± 1.7) mg/L vs (2.5 ± 1.4) mg/L] (P ＜ 0.05);the levels of hemoglobin and hs-CRP in observe group were significantly reduced after 6 months of treatment [(132 ± 9) g/L, (3.8 ± 1.1) mg/L] (P ＜ 0.05).Conclusions CPAP can significantly reduce the levels of hemoglobin and hs-CRP in severe OSAHS patients;hemoglobin and hs-CRP can be used as indexes to judge the severity of inflammation and curative effect in severe OSAHS patients.
Keywords：Obstructive sleep apnea-hypopnea syndromeHemoglobinHigh sensitivity C-reactive proteinContinuous positive airway pressure
Publication Date：2015-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1588-1590 )