Mitral valve morphological changes and cardiac function in different severities of mitral regurgitation assessed by echocardiography

Jin Can; Li Xinming; Ning Zhongping; Zhao Zhihong

doi:10.3760/cma.j.issn.1673-4777.2015.10.006

Abstract：Objective To assess the mitral valve morphological changes and cardiac function in different severities of mitral regurgitation.Methods Totally 78 patients with different severities of mitral regurgitation from October 2012 to August 2013 underwent echocardiography;they were divided into mild regurgitation group (35 cases),moderate regurgitation group (27 cases) and severe mitral regurgitation group (16 cases).The echocardiography parameters were compared among three groups.Results The left atrial diameter and left ventricular end diastolic diameter were statistically different between different groups [(35 ± 6) mm vs (42 ± 6) mm vs (47 ±8) mm,(47 ± 10) mm vs (51 ±7) mm vs (58 ±6) mm];the left ventricular end systolic diameter was significantly higher in severe mitral regurgitation group than that in mild and moderate regurgitation group [(39 ± 6) mm vs (33 ± 9),(36 ± 7) mm,P ＜ 0.05];the left ventricular ejection fraction had no significant differences among the three groups (P ＞ 0.05);the mitral annular area was significantly greater in severe mitral regurgitation group than that in mild and moderate regurgitation group [(940 ±281) mm2 vs (642 ±276),(685 ± 247) mm2,P ＜ 0.05];cusps junction depth relative to the annulus was significantly greater in moderate and severe regurgitation group than that in mild regurgitation group [(8.5 ± 2.2),(8.8 ± 1.8)mm vs (7.1 ± 2.3) mm,P ＜ 0.05].Conclusion The mitral valve ring morphology and cardiac function are different in different severities of mitral regurgitation;before percutaneous mitral valvuloplasty,echocardiography can guide the operation mode and patients with severe mitral regurgitation maybe benefit more from percutaneous mitral annuloplasty.