Correlation between peripheral arterial atherosclerosis and cardiac diastolic function
Li Xiaoming
Zhang Chun
Niu Baorong
Wu Shan
Yang Ya
Abstract：Objective To evaluate the correlation between peripheral arterial atherosclerosis and cardiac diastolic function.Methods Totally 235 elderly patients with peripheral arterial atherosclerotic plaque diagnosed by ultrasound were enrolled and divided into mild dysfunction group (114 cases) and moderated dysfunction group (131 cases) according to the cardiac diastolic dysfunction grade.The brachial-ankle pulse wave-velocity (baPWV),ankle-brachial index (ABI) and cardiac diastolic function were assessed and compared between the two groups.The Spearman analysis was performed to evaluate the correlation between cardiac diastolic function with baPWV and ABI.Results There were no significant differences in baPWV and ABI between the two groups (P ＞ 0.05).In mild dysfunction group,the indices of cardiac diastolic function such as mitral valve peak early diastolic blood flow velocity/mitral valve late diastolic flow velocity (E/A) and E/mitral annulus velocity (E/E') were both correlated with baPWV (r =-0.682,0.724) and ABI (r =-0.512,0.553) (P ＜ 0.05).In moderate dysfunction group,E/A and E/E'were not correlated with baPWV and ABI (P ＞ 0.05),while were correlated with age (r =-0.452,0.522) and uric acid (r =-0.434,0.487) (P ＜ 0.05).Conclusion The cardiac diastolic function shows a correlation with peripheral vascular elasticity in mild cardiac diastolic dysfunction patients.
Keywords：Ventricular-vascular couplingAtherosclerosis plaqueBrachial-ankle pulse wave-velocityAnkle-brachial index
Publication Date：2015-06-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 785-787 )