Value of anti-thyroglobulin antibody detection in diagnosis of differentiated thyroid cancer
Guan Leihong
Liu Hui
Chen Shen
Wang Yalin
Wang Yichen
Abstract：Objective To observe the value of anti-thyroglobulin antibody(TGA) detection in the diagnosis of differentiated thyroid cancer (DTC) at community hospital.Methods Totally 98 followed-up patients with thyroid nodule who were diagnosed by ultrasound from January 2000 to December 2013 and subsequently received operation in the superior hospital were enrolled.According to the results of pathology,the patients were divided into malignant group (35 cases of DTC) and benign group [63 cases of nodular goiter (NG) or thyroid adenoma (TA)].The level of TGA level and positive rate of TGA were assessd and compared between the two groups.Results The TGA level and positive rate of TGA in malignant group were significantly higher than those in benign group [21.7 (9.6,126.8) kU/L to 14.6 (8.1,25.0)kU/L,37.1％ (13/35) to 11.1％ (7/63)] (P＜ 0.05).Conclusion Anti-TgAb detection is useful for early diagnosis of DTC at community hospital.
Keywords：Anti-thyroglobulin antibodyCommunity healthDifferentiated thyroid cancer
Publication Date：2015-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 642-644 )