Insulin pump treating poor glucose control patients with type 2 diabetes mellitus
Chen Yan
Zhao Li
Abstract：Objective To assess the efficacy and safety of insulin pump therapy treating poor glucose control patients with type 2 diabetes mellitus (T2DM).Methods Totally 100 poor glucose control patients with T2DM were selected.A randomized and multiple insulin injection-controlled study was performed.T2DM patients were randomly assigned into oberstivation group (n =50) and control group (n =50).Patients in observation group received insulin pump therapy,while patient in control group received the treatment of multiple subcutaneous insulin injection.The blood glucose at six time points,hospitalization days,average insulin dose and incidence of hypoglycemia were compared.Results No significant differences of blood glucose between groups were observed (P ＜ 0.05) at baseline.After intensive therapy,the fasting blood-glucose was significantly decreased in both groups (before treatment,before breakfast,2 h after breakfast,2 h after lunch,after dinner for 2 h before bedtime,3:00 am blood glucose in control group were 14.2±3.4,18.9±2.9,16.5±3.4,16.4±3.8,12.4±2.2,8.9 ± 3.2 mmol/L ;after treatment was 6.9 ± 1.3,7.4 ± 1.7,8.2 ± 1.6,8.6 ± 1.8,8.3 ± 1.5,7.8 ± 1.5 mmol/L;before treatment,before breakfast,2 h after breakfast,2 h after lunch,after dinner for 2 h before bedtime,3∶00 am blood glucose inobservation group were 14.3 ± 3.2,18.0 ± 4.8,16.9 ± 4.5,16.2 ± 3.7,12.2 ± 2.6,9.9 ± 1.5 mmol/L;after treatment was 6.0 ± 1.2,6.6 ± 1.5,7.1 ± 1.4,7.5 ± 1.6,7.2 ± 1.3,6.6 ± 1.1 mmol/L; all P ＜ 0.01).The average consumption of insulin per day was (43.9 ± 3.6) U/d in observation group,significantly lower than that in control group (P ＜ 0.001).The hospitalization time was (7.1 ± 2.1) days in observation group,statistically significant lower than that in control group (P ＜ 0.01) ; the incidence of hypoglycemia in observation group was 6.0％ (3/50),statistically lower than that in control group (P ＜ 0.01).Conclusion Both insulin pump and multiple subcutaneous insulin injection are effective in blood glucose control among T2DM patients with poor glucose control.
Keywords：Diabetes mellitus,type 2Insulin pumpMultiple subcutaneous insulin injectionPoor glucose control
Publication Date：2015-02-28
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 196-199 )