The clinical study of povidone iodine cryopreservation technique in self-skull repairing operation
Zhuang Minghua
Luo Cheng
Chen Bin
Abstract：Objective To study about the long-term effect of povidone iodine cryopreservation technique in self-skull repairing operation.Methods Totally 30 patients taken craniocerebral surgical operation participated in this research voluntarily.The skull bone flap was removed during the neurosurgery and was cryopreserved with povidone iodine preservative liquid.Before preservation,the skull bone flap was cleaned with 0.9％ sodium chloride solution,and the liquid after washing was collected for microbiological analysis.The skull bone flap would be cryopreserved for 3 to 6 months and used for self-skull repairing operation.Results In total 30 cases,wound infection occured in 1 case and the repaired skull bone flap was removed later; 1 dead case had intracranial infection after the ventricle peritoneal drainage treating postoperative hydrocephalus; postoperative extradural hematoma was in 1 case via CT examination 5 hours after the original neurosurgery and the patient received the removal operation of epidural hematoma; small amount of effusion under the scalp appeared in 1 case and self-absorption was observed later; no infection,subdural or extradural hematoma,skin flap necrosis were observed in other 26 cases.The postoperative CT check showed the good skull anatomical reset.According to the follow-up from 1 month to 5 years after the surgery,all patients well recovered.Conclusion The method of applying povidone iodine cryopreservation technique to preserve the skull bone flap for self-skull repairing is reliable,safety and convenient.
Keywords：Skull defectPatient's skull bone flapRefrigerating povidone Iodine preservative fluid
Publication Date：2015-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 192-195 )