The relation between white matter lesions of different parts of brain after acute cerebral infarction and depressive disorder
Jiang Lijie
Yu Min
Zhou Ying
Hou Yu
Lou Wei
Abstract：Objective To evaluate the relationship between white matter lesions(WML) of different parts of brain after acute cerebral infarction and depressive disorder.Methods The clinical data of 97 patients with acute cerebral infarction were analyzed.All patients were divided into 2 groups according to with or without WML.The differences of Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) between 2 groups were analyzed.The WML group was scored using the semiquatitative rating scale of Scheltens Rating Scale(Scheltens).The correlation between the scheltens of lateral ventricle,frontal lobe,parietal lobe,temporal lobe,occipital lobe,basal ganglia,cerebella,brainstem and HAMD were observed.Results In WML group,the scale of HAMD was 10 ±6 and HAMA was 11 ±4.In without WML group,the scale of HAMD was 6 ±4 and HAMA was 9 ±3.There were significant differences of HAMA and HAMD between WML group and without WML group.HAMD was positively correlated with total scores of total Scheltens scales(4.39 ± 0.49),frontal (2.76 ± 0.43),occipital white matter(1.61 ± 0.49) and frontal periventricular hyperintensities (2.85 ± 0.36) (r =0.395,P =0.002;r =0.439,P =0.001 ;r =0.247,P =0.005 ;r =0.385,P =0.003).Conclusion WML of different parts after acute cerebral infarction is positively correlated with depressive disorder,especially in frontal white matter.
Keywords：White matter lesionsDifferent partsDepression
Publication Date：2015-02-28
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 185-187 )