The therapeutic efficacy of pediatric paracetamol combined with ribavirin aerosol in children with acute upper respiratory tract infection
Tao Linhui
Guan Minchang
Peng Cangjiao
Jin Xiaohong
Abstract：Objective To explore the therapeutic efficacy of pediatric paracetamol combined with ribavirin aerosol in children with acute upper respiratory tract infection.Methods One hundred and thirty-eight children with acute upper respiratory tract infection were divided into control group (69 cases) and the treatment group (69 cases).Patients in control group were given ribavirin granules.Patients in treatment group were given pediatric paracetamol.Thetherapeutic effects in both groups were evaluated after 5 days.Results After treatment,the effective rate of the treatment group was significantly higher than that of the control group [95.7％ (66/69) vs 76.8％ (53/69)],there was a statistically significant difference (x2 =13.80,P ＜ 0.05).After treatment,the fever lasting time,runny nose relief time,stuffy nose remission time and cough relief time in the treatment group were shorter than those in the control group[(2.4±0.5)d vs (2.9 ±0.6)d,(2.8 ±0.7)d vs (3.8 ±0.9)d,(3.2 ± 0.8) d vs (3.8 ± 0.9) d,(3.6 ± 1.2) d vs (4.9 ± 1.3) d] ; there were statistically significant differences (P ＜ 0.01).During the treatment,the control group had 1 cases of leukopenia and the treatment group had no adverse reactions.Conclusion Pediatric paracetamol combined with ribavirin aerosol are effective in the treatment of acute upper respiratory tract infection in children.
Keywords：Respiratory tract infectionsPediatric paracetamolRibavirinTreatment outcome
Publication Date：2015-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 177-179 )