Efficacy of combination therapy of mycoplasma pneumonia: a Meta analysis
Huang Yuying
Qiu Zhongyan
Zhu Sigang
Abstract：Objective To discuss the clinical efficacy of Chinese and Western medicine inmycoplasma pneumonia in children.Methods Randomized controlled trials (RCTs) on western medicine versus traditional Chinese combined with Western medicine treating children mycoplasma pneumonia were identified according to the inclusion and exclusion criteria.Methodological quality of included studies was accessed.Meta-analysis was then performed using RevMan 4.2 software.Pooled odds ratio (OR),weighted mean difference (WMD) and 95％ confidence interval (CI) were calculated.20 randomized controlled domestic researches were gathered.Results Cure rate and effective rate in the experimental group were better than those in the control group(OR =2.92,95％ CI:2.29 to 3.74,P ＜0.01).Inefficiency in the experimental group was lower than in control group; the difference was statistically significant (OR =0.20,95％ CI:0.12 to 0.34,P ＜ 0.01) ; rale disappearance time,cough disappearance time and cooling time in the experimental group were shorter than those in control group(WMD =-2.22,95％ CI:-2.43 to-2.01,P＜0.01),(WMD =-1.61,95％ CI:-2.35 to-0.86,P＜0.01),(OR=-0.90,95％ CI:-1.43 to-0.37,P =0.0008).The incidence of adverse reactions in the experimental group was lower than that in the control group; the difference was statistically significant,(WMD =0.16,95％ CI:0.05 to 0.48,P =0.001).Conclusion Treatment of mycoplasma pneumonia in children with Chinese and Western Medicine can significantly increase the efficiency of recovery; the non-efficiency and the incidence of adverse reactions can be significantly reduced.
Keywords：Mycoplasma pneumoniaChinese and Western MedicineAzithromycinErythromycinMeta analysis
Publication Date：2014-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：7( 1585-1591 )