Impact of hypertension on young women with acute myocardial infarction and the relation between hypertension and the severity of coronary artery lesions

doi:10.3760/cma.j.issn.1673-4777.2014.11.001

Abstract：Objective To investigate the characteristics of hypertension and the relation between hypertension and the severity of coronary artery lesions in young women with acute myocardial infarction (AMI).Methods We retrospectively studied 64 young women with acute myocardial infarction.All patients were admitted to hospital from Jun.2003 to Dec.2013 and undergone coronary angiography; the clinic and coronary angiographic features were assessed.According to the result of coronary angiography,the patients were divided into two groups:the single-vessel-lesion and the multiple-vessel-lesion.The relation among hypertension and acute myocardial infarction and severity of coronary artery disease were observed.Results ①The ratio of patients with hypertension in AMI group was significantly higher than in non-CHD group[56.2％ (36/64) vs 8.3％ (5/60),P ＜0.05].In AMI patients,the ratio of patients with hypertension in the single-vessel-lesion group was significantly lower than in the multiple-vessel-lesion group [47.8 ％ (22/46) vs 77.8 ％ (14/18),P ＜ 0.05].②Applying Logistic regression analysis,hypertension(OR =16.173,95％ CI:4.130-63.328),hemoglobin (OR =1.039,95％ CI:1.002-1.078) and uric acid (OR =1.008,95％ CI:1.001-1.016) were independent risk factors(P ＜ 0.05) for young women with AMI.③In AMI patients,the ratio of patients with hypertension in the multiple-vessel-lesion group was significantly higher than that in patients without hypertension in the multiple-vessel-lesion group [38.9％ (14/36)vs 14.3％ (4/28),P ＜ 0.05].In ST-segment elevation myocardial infarction patients,the ratio of patients with hypertension in the single-vessel-lesion group was significantly lower than in the multiple-vessel-lesion group [46.2％ (18/39) vs 77.8％ (14/18),P ＜ 0.05].Conclusion Hypertension is a risk factor for young women with AMI,and coronary artery lesions are more severe in hypertension patients with AMI.