Study of serum sex hormone levels and stopping age sexual activity in patients with Alzheimer's disease
Abstract：Objective To explore serum hormone levels and stopping age sexual activity in patients with Alzheimer's disease(AD).Methods All 126 cases of AD patients were as the AD group,including 66 women and 60 men with Alzheimer's disease.Normal control group included 120 cases,including 60 women and 60 men.Fasting venous blood was taken for 3 ml in morning and sex hormones included follicle stimulating hormonl(FSH),luteinizing hormone(LH),estradiol(E2),testosterone,progesterone and prolactin(PRL).Results E2 was lower in women with AD than in normal control[(9.4 ± 2.8) ng/L vs (18.9 ± 3.0) ng/L] and there was a statistical difference (P ＜ 0.05) ; testosterone in men with AD was lower than in normal control [(2.5 ± 1.0) μg/L vs (4.8 ± 1.6) μg/L],there was also statistical difference(P ＜ 0.05).FSH,LH,testosterone,progesterone,PRL of AD women comparing with normal women was not statistically difference (P ＞ 0.05).FSH,LH,E2,progesterone,PRL of AD men comparing with normal men was not statistically difference(P ＞ 0.05).AD female sexual activity ceases age significantly earlier than the normal control group of women[(56 ± 5) years old vs (68 ± 6) years old] (P ＜0.05) ; male AD patients sexual activity stopped age significantly earlier than the normal control group of men [(66 ± 5) years old vs (72 ± 7) years old] (P ＜ 0.05) ; female AD patients sexual activity stopped at earlier ages than men AD patients(P ＜ 0.05).Conclusions Stopping age sexual activity of people with AD is earlier than that of normal people.Serum hormone levels and early stopping age sexual activity maybe risk factors of AD.
Keywords：Alzheimer's diseaseSex hormoneStopping age sexual activity
Publication Date：2014-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1464-1467 )