Comparison of long-term outcomes of pulmonary vein isolation with or without additional linear ablation in paroxysmal atrial fibrillation patients with left atrial enlargement
Abstract：Objective To compare the long-term outcomes of circumferential pulmonary vein isolation (CPVI) and CPVI plus linear ablation in paroxysmal atrial fibrillation(PAF) patients with left atrium(LA) enlargement.Methods One hundred and eighty-eight patients of PAF with LA dimention≥40 mm were included,and CPVI was performed followed by burst pacing induction.CPVI group included 132 cases with sinus rhythm restored after CPVI and no arrhythmia induced.CPVI + linear ablation group included 56 cases among whom AF was not terminated or atrial arrhythmia was induced with mitral isthmus,LA roofline and cavo-tricuspid isthmus ablated.All patients were followed up for 3 years.Results Procedure time [(205 ± 67) min vs (142 ± 45) min,P ＜0.01] and X-ray exposure time [(40 ± 16) min vs (28 ± 21) min,P ＜ 0.01] were significantly longer in CPVI + linear ablation group.One-year successful rate after single procedure was lower in CPVI + linear group [66.1％ (37/56) vs 79.5 ％ (105/132),P =0.047],but no significant difference was observed regarding 3-year successful rate after single procedure [60.9％ (28/46) vs 59.2％ (78/132),P =0.857],as well as 3-year cumulative successful rate(69.2％ vs 66.7％,P =0.755).Conclusions In PAF patients with LA enlargement,the shortterm successful rate is lower in patients undergoing CPVI plus additional linear ablation than that in CPVI,but the long-term outcomes are equivalent.
Keywords：Paroxysmal atrial fibrillationCatheter ablationLong-term outcome
Publication Date：2014-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1089-1093 )