Risk factors and angiographic characteristics in both young and elderly women with coronary heart disease
Li Min
Mi Shuhua
Zhou Yun
Chen Qing
Zhang Xiaoxia
Su Gong
Abstract：Objective To investigate clinical characteristics of women with coronary heart disease (CHD).Methods Clinical and coronary angiographic features were compared among 248 young women with CHD[60 cases with acute myocardial infarction (AMI)] and 240 elderly women with CHD(57 cases with AMI) ; all patients underwent coronary angiography.Results (1)The proportion of hypertension,diabetes and hypercholesterolemia in young women was higher than that in elder women [52.4％ (130/248) vs 70.8％ (170/240),16.9％ (42/248) vs 56.7％ (68/240),25.8 ％ (64/248) vs 45.0％ (108/240)] (all P ＜ 0.05).(2) The proportion of coronary angiography single vessel disease in young women was higher than that in elder women [76.6％ (190/248) vs 35.0％ (84/240)] (P ＜0.05).74 patients(30.8％) had three vessel disease in elderly women,which was higher than that in young women [13.3％ (8/248) vs 35.1％ (20/240)] (P ＜ 0.05).(3) Drug therapy and single vessel coronary percutaneous intervention in young women were higher than those in elderly women [29.8％ (74/248) vs 16.3％ (39/240),82.6％ (133/248) vs 62.8％ (113/240)] (P ＜0.05).(4)Totally sixty patients(24.2％) had AMI in young women group; fifty-seven patients(23.8％) had AMI in elder women group; there were no difference in the two groups.40 patients (66.7％)in young women group with AMI had single vessel disease and 22 patients (38.6％) in elderly women group with MI had single vessel disease (P ＜ 0.05) ;8 patients (13.3％) in young women group with MI had three vessel disease and 20 patients (35.1％) in elder women group with MI had three vessel disease (P ＜ 0.05).(5) Logistic regression analysis showed that essential hypertension,body mass index,triglyceride and family history of coronary heart disease were independent risk factors for young women with AMI[odds ratio(OR) =22.182,95％ cofidence interval(CI):5.590-96.182,P =0.000 ;OR =0.892,95 ％ CI:0.858-0.969,P =0.004 ; OR =0.762,95 ％ CI:0.612-0.901,P =0.003 ; OR =0.357,95％ CI:0.158-0.418,P =0.000].Essential hypertension and diabetes mellitus (DM) were independent risk factors for elderly women with MI(OR =3.027,95％ CI:1.799-5.102,P =0.000; OR =1.678,95％ CI:1.004-2.811,P =0.040).Conclusions Yong women with CHD has relatively less coronary risk factors than elder women.Coronary angiography shows that pathological changes in young women are relatively limited.Hypertension,body mass index,high triglycerides and family history of CHD risk factors in young women with myocardial infarction.Hypertension and diabetes are risk factors in elderly women with myocardial infarction.
Keywords：Coronary heart diseaseRisk factorCoronary angiographyWomen
Publication Date：2014-07-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 929-933 )