A study of prognosis of patients with acute chest pain of emergency department by global registry of acute coronary events or thrombolysis in myocardial infarction risk stratification
Yin Chengqian
Yao Limei
Zhang Jingmei
Li Zhizhong
Gao Yun
Abstract：Objective To investigate global registry of acute coronary events(GRACE) score,thrombolysis in myocardial infarction(TIMI) score in patients with undifferentiated chest pain.Outcomes included emergency admission,emergency coronary artery interventional therapy,30 days of death and other cardiovascular adverse event prediction.Methods The clinical data of 536 patients with acute chest pain were retrospectively analyzed.30 days death and other adverse events were analyzed.Score and outcome were compared using receiver operating characteristic curve analysis.Results The average age of patients with chest pain in the emergency department was (56 ± 13) years,emergency admission in 319 cases (59.5％) ; 30 days of death in 45 cases (8.4％).Compared with TIMI risk score,GRACE risk score could independently predict acute hospitalization odds ratio(OR):1.02,95％ confidence interval(CI):1.01-1.03,P=0.01),30 d death (OR; 1.05,95％ CI:1.04-1.07,P＜ 0.01) and emergency PCI (OR:1.02,95 ％ CI:1.01-1.03,P ＜ 0.01) risk ; also which ROC of hospitalization rate(0.873,95％ CI:0.843-0.903),30 day mortality(0.654,95％ CI; 0.573-0.736),PCI(0.746,95％ CI:0.705-0.787) rate and other MACE events (0.651,95％ CI:0.577-0.725) were statistically significant (P ＜ 0.01).The GRACE risk score was more sensitive than the TIMI risk score.Conclsion Compared with the TIMI score,GRACE score can be more effective determining the death rate at 30 days and the prognosis of emergency PCI in emergency patients with acute chest pain.
Keywords：Cardiovascular diseaseAcute chest painGlobal registry of acute coronary events risk scoreThrombolysis in myocardial infarction risk scoreMortalityCardiovascular adverse eventsPrognosis
Publication Date：2014-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 631-635 )