Analgesic effect analysis of dyclonine hydrochloride on anorectal surgery
Huang Chun
Abstract：Objective To explore the analgesic effect of hydrochloric dyclonine gauze used during anorectal surgery.Methods Fifty patients with anorectal surgery received in our department were randomly divided into dyclonine hydrochloride group and methylene blue group with 25 cases in each group.The dyclonine hydrochloride group were treated with dyclonine hydrochloride gauze for postoperative dressing,the methylene blue group were treated with methylene blue for postoperative analgesic,the analgesic effect of 24 hours to a half months after surgery were observed.Results The total effective rate of dyclonine hydrochloride group was 92.0％ (23/25),which was significantly higher than that of methylene blue group [80.0％ (20/25)],the difference was statistically significant (P ＜ 0.05).In postoperative 24 h,24-72 h and 72 h-1 week,the pain cases in dyclonine hydrochloride group were 10 cases,1 case,0 case,which were significantly higher than methylene blue group 22 cases,16 cases,5 cases(x2 =12.5,20.1,5.6,P ＜0.05).The pain disappeared time,Edema subsiding swelling time and wound healing time in dyclonine hydrochloride group were (5.4 ± 1.2) h,(4.3 ± 0.9) h,(14.4 ± 3.7) h,which were significantly shorter than those in methylene blue group[(8.9 ± 2.7) h,(7.8 ± 1.6) h,(18.9 ± 4.2) h,t =5.9,9.5,4.0,P ＜ 0.05].Conclusion The dyclonine hydrochloride as a local anesthetic for anorectal postoperative analgesia has some advantages such as rapid onset,better analgesic effect and long-term cure rate.
Keywords：Anorectal surgeryDyclonine hydrochlorideLocal anestheticPostoperative analgesia
Publication Date：2014-04-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 516-518 )