Curative effect observation of bronchitis pneumonia by the treatment of different methods of abstention with phentolamine

Mi Wenyu; Wang Weihong; Chen Huangzhen

doi:10.3760/cma.j.issn.1673-4777.2014.04.013

Abstract：Objective To observe the clinical curative effect in children's bronchitis pneumonia accompanied with cardiac failure by the treatment of the two different methods of abstention with phentolamine.Methods Eighty-one cases in children's pneumonia accompanied with cardiac failure were stochastically divided into treatment group 1(24 cases,treated by infusion with phentolamine) and treatment group 2(30 cases treated by continuos pump with phentolamine) and control group(27 cases,without phentolamine).The control group was conventionally treated by anti-infection,antiasthmatic effect and cardiac strength.Based on the treatment above,treatment group 1 took the intravenous injection into murph's dropper with phentolamine,and group 2 took the intravenous infuseion with phentolamine.The clinical efficacy of the three groups of patients,cough disappearance time,wheezing disappearance time,pulmonary rales disappeared time and adverse reactions were observed.Results Cough disappearance time had no significant difference in treatment group 1 and treatment group 2.Wheezing disappeared time and pulmonary rales disappeared time in the treatment group 2 were shorter than those in the treatment group 1 [(5.9±0.8)d vs (6.8±1.1)d,(6.3±0.9)dvs (6.8±0.9)d,P＜0.05].Effective rate in the treatment group 2 was higher than that in the control group and treatment group 1 [96.7％ (26/30) vs 91.7％ (22/24),85.2％ (23/27)]; effective rate in the treatment group 1 was higher than that in the control group; differences were statistically significant(all P ＜0.05).Conclusions Children with bronchial pneumonia and congestive heart failure treated by intravenous drip infusion pump phentolamine,wheezing disappeared time and pulmonary rales disappeared time are shortened.There are no adverse reactions such as nasal resistance,irritability,increased heart rate.