Correlation between prognosis of short-time transient ischemic attack and cerebral artery stenosis

Zhang Yan; Niu Xiaoyuan; Xu Wei

doi:10.3760/cma.j.issn.1673-4777.2014.03.014

Abstract：Objective To explore the correlation between prognosis of transient ischemic attack(TIA) with the characteristic of cerebral arteries stenosis and plaque. Methods A retrospective clinical analysis was performed on the clinical data from 87 patients with the first time attack of TIA. The patients were divided into favorable prognosis group, frequent attacks group and cerebral infarction group. Results Favorable group had 34 cases, frequent attacks group had 37 cases and cerebral infarction group had 8 cases. In favorable group, there were mild stenosis 77.4%(24/31) position and calcific plaque 51.4%(18/35); the least was cerebral infarction group(mild stenosis 56.4%, calcific plaque 12.9%). The severe stenosis, occlusion and soft plaque in favorable group was least(severe stenosis 3.2%, occlusion 3.2%, soft plaque 14.3%); the highest was cerebral infarction group(severe stenosis 15.4%, occlusion 17.9%, soft plaque 38.7%). The positive rate nature of plaques and the stenosis degree of artery were significantly different among the three groups(all P＜0.05). The CCA was the frequent stenosis in anterior circulation at favorable group[38.9%(7/18], the ICVA was the frequently stenosis in posterior circulation at favorable group [30.8%(4/13)],the MCA was the frequently stenosis in posterior circulation between frequent attacks group [32.5%(13/40)] and cerebral infarction group [36.8%(7/19)]; the ECVA was the frequently stenosis in posterior circulation between frequent attacks group [36.0%(9/25)]and cerebral infarction group [35.0%(7/20)](P>0.05). Conclusions In this study the short time prognosis of TIA is associated with the stenosis degree of artery and nature of plaques. The severe stenosis and unstable plaque suggest poor prognosis.