Clinical observation on Chuanxiong qingnao particles in the treatment of vertebra-basilar ischemic vertigo
Hu Daihuai
Abstract：Objective To explore clinical efficacy of Chuanxiong qingnao particles in the treatment of cerebral vertigo caused by vertebrobasilar insufficiency.Methods All 135 patients of vertebra-basilar ischemic vertigo in the first affiliated hospital of Hu'nan Chinese medicine university from February 2013 to June 2013 were selected and divided into observation group (85 ceases) and control group (50 ceases),observation group was given Chuanxiong qingnao particles,and control group was given halo carbamazepine capsules,course of treatment of two groups were 4 weeks.Symptoms,Doppler ultrasound results and blood rheology before and after treatment of two groups were observed.Results The total effective rate in the observation group was 97.6％ (83/85),significantly higher than that in the control group [80.0％ (40/50)] ; the difference was statistically significant (P ＜0.05) ; the total effective rate of vertigo,tinnitus,nausea,heavy head in observation group after treatment were significantly better than those in the control group [100.0％ (38/38) vs 81.8％ (18/22),100.0％ (30/30) vs 83.3％(15/18),100.0％ (6/6) vs 75.0％ (3/4),85.7％ (6/7) vs 75.0％ (3/4),75.0％ (3/4) vs 50.0％ (1/2)] (P ＜ 0.05 or P ＜ 0.01).There were significant differences on blood flow velocity of middle cerebral artery and anterior cerebral artery in observation group after treatment [(13 ± 3) mm/s vs (23 ± 4) mm/s,(8.2 ±2.2) mm/s vs (3.8 ± 3.2) mm/s] (P ＜ 0.05).Blood flow velocity of middle cerebral artery and anterior cerebral artery in observation group after treatment were lower than those of control group [(25 ± 4),(13.2 ±3.5) mrn/s] (P ＜0.05).There were significant differences on whole blood viscosity of low,high and midst shear in observation group after treatment [(4.6 ± 0.3) mPa/s vs (3.0 ± 0.2) mPa/s,(12.0 ± 1.1) mPa/s vs (13.6 ±1.1) mPa/s,(14.2 ± 1.6) mPa/s vs (17.1 ± 1.9) mPa/s] (P ＜ 0.05).Whole blood viscosity of low,high and midst shear in observation group after treatment were lower than those in control group [(4.8 ±0.3),(12.6 ±1.1),(15.0±1.7) mPa/s]; there were significant differences (P＜0.05).Conclusion Chuanxiong qingnao particles in the treatment of cerebral vertigo caused by vertebrobasilar insufficiency is effective and safe.
Keywords：Vertebrobasilar insufficiencyCerebral vertigoChuanxiong qingnao particles
Publication Date：2014-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 54-57 )