Relationship of carotid intima-media thickness with large artery atheroscelerosis and small artery occlusion ischemic stroke
Gao Haining
Shaliya Naseer
He Xiaoyan
Li Hongyan
Abstract：Objective To investigate the role of athersclerosis in the pathogenesis of large artery atherocelerosis and small artery occulsion ischemic stroke.Methods One hundred and ninety-seven acute ischemic stroke patients were classified into large artery atherosclerosis in acute ischemic stroke (LAA group,63 patients) and small artery occlusion model of acute ischemic stroke (SAO group,134 patients)according t6 acute stroke treatment criteria,imaging and clinical features.All patients underwent B-Mode ultrasonography of both carotid arteries and intima media thickness (IMT),C-reactive protein (CRP) and blood fat.Results IMT was higher in patients with LAA (0.88 ± 0.34) mm than in patients with SAO (0.76 ± 0.22) mm.CRP was higher in LAA group [4.63 (2.29,11.99) mg/L vs 2.98 (1.82,6.70) mg/L].Hyperhomocysteinaemia (HCY),lipoprotein a,blood glucose and glycated hemoglobin were not significantly different between two groups [(6.4 ± 2.3) mmol/L vs (2.0±0.8) mmol/L,(6.4 ± 1.6)％ vs (6.1 ± 1.2)％,(3.6 ± 1.1)g/L vs (3.3 ±0.9)g/L,(22 ± 11) μmol/L vs (20 ± 11) μmol/L,(305 ± 181) mg/L vs (267 ± 143) mg/L,(1.5 ± 0.8) mmol/L vs (1.8 ± 1.5) mmol/L,(4.1 ± 1.1) mmol/L vs (4.1 ± 1.1) mmol/L,(1.33 ± 0.29) mmol/L vs (1.46 ± 0.64) mmol/L,(2.0 ±0.9) mmol/L vs (2.0 ± 0.8) mmol/L,P ＞ 0.05].Conclusion IMT and CRP are higher in LAA patients than in SAO patients,indicating that LAA and SAO have a different pathogenesis.
Keywords：Ischemic strokeAtherosclersoisIntimia-media thickness
Publication Date：2014-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 51-54 )