Effect of metabolic syndrome on the severity and prognosis of acute pancreatitis
WANG Xiao-yue
LI Ya-jun
Abstract：Objective To investigate the effect of metabolic syndrome on acute pancreatitis.Methods The clinical data of 82 acute pancreatitis(AP)patients with metabolic syndrome(group A)and 86 AP patients without metabolic syndrome(group B) were retrospectively analyzed.Ranson score,Balthazar CT grading,serum calcium and blood high-sensitivity C-reactive protein(hs-CRP),blood oxygen partial pressure (artery)(PaO2),time of abdominal pain relieving,fasting time,blood amylase recovery time,hospital stay,local complications and systemic complications of two groups were compared.Results Compared with group B,Ranson score and Balthazar CT grade score and hs-CRP in group A were higher[(3.4 ± 1.0) scores vs (2.3 ±0.8) scores,(3.0 ±0.7) scores vs (2.2 ±0.8)scores,(33.1 ±2.2)mg/L vs (30.4 ±4.1)mg/L].Blood calcium and PaO2 were lower[(1.87 ±0.29)mmol/L vs (2.10 ±0.26)mmol/L,(71 ±6)mm Hg(1 mm Hg=0.133 kPa) vs (75 ±6) mm Hg] (all P＜0.01).The relief time of abdominal pain,the fast time,the normalized time of serum amylase and in-hospital days in group A were longer than those in group B; local complications and systemic complications was higher in group A [(14.6 ± 2.8) d vs (10.8 ±3.4)d,(8.7 ±4.0)d vs (6.4 ± 1.9)d,(7.2 ± 1.5)d vs (6.3 ± 1.7)d,(7.3 ±3.0)d vs (6.3 ±2.0)d] (P ＜ 0.05 or P ＜ 0.01).The incidence of local and systemic complications in group A were higher than those in group B (34.1％ (28/82) vs 19.8％ (17/86),x2 =4.425,P=0.035; 37.8％ (31/82) vs 23.3％ (20/86),x2 =4.203,P=0.040).Conclusion Metabolic syndrome is closely correlated with the prognosis and severity of acute pancreatitis.
Keywords：Acute pancreatitisMetabolic syndromePrognosis
Publication Date：2013-12-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1745-1746,1749 )