Intervention of Chinese medicine in hematopoietic system in rats caused by radiation
QU Bin
ZHANG Rong
YANG Yun-shuang
LI Yan-hui
Abstract：Objective To observe the intervention of Chinese medicine in hematopoietic system in rats caused by radiation.Methods Totally 150 healthy male Wister rats were divided randomly into 5 groups:normal group,radiation model group,radiation bazhen medicine group,radiation liuwei medicine group and radiation self-side medicine group,with 30 rats in each group.Except blank group,the remaining four groups received 7 Gy of 60Co γ-ray irradiation.After irradiation,the abdominal aortic blood were collected and determined using automatic biochemical analyzer; peripheral blood micronucleated reticulocye was observed; bone marrow specimens of pathological morphological changes and pathological changes were observed using electron microscopy.Results Afterradiation,the white blood cells of each experimental group were decreased and neutrophil ratio increased.After 60Co γ-ray irradiation,the bodies showed inflammatory response.The apparent collapse was observed in rat by radiation in electron microscope.Neutrophils increased significantly.Conclusions Radiation can cause the change of hemogram and bone marrow of body structure.The prescription of traditional Chinese medicine six taste glutinous rehmannia pill has good radiation protection effect on severe acute radiation sickness and plays a role in the prevention and treatment.Prescriptions of anti-radiation from can provide effective protection on hematopoiesis system and promote blood regeneration.
Keywords：Chinese medicineRadiationRatsMarrowHematopoietic function
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1734-1737 )