Clinical study of tegafur treating elderly advanced gastric cancer
ZHOU Qin
ZHU Hai-peng
HU Jun
WU Ke-xiong
Abstract：Objective To evaluate the efficacy and toxicity of tegafur for elderly advanced gastric cancer.Methods Twenty-three elderly patients with advanced gastric cancer were treated with tegafur capsule 40-60 mg each time,two times perday.The evaluation of efficacy and toxicity were performed on all patients after 2 cycles.Results Of the 23 patients,there were 0 (0％) complete remission (CR),8 (34.7％) partial remission (PR),9 (34.7 ％) stable disease (SD) and 6 (26.1％) progression disease (PD).The total response rate (CR + PR) was 34.7％.The disease control rate(CR + PR + SD) was 73.9％.The major toxicities included myelo suppression,gastrointestinal reaction and cutaneous pigmentation.Conclusion Tegafur is safe and effective in the treatment of advanced gastric cancer,especially for old and frail patients.
Keywords：Gastric tumorElderlyTegafurChemotherapy
Publication Date：2013-12-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 1726-1727 )