Correlation between cardiovascular risk factors and coronary artery lesion in postmenopausal women with coronary heart disease
KANG Yun-peng
LIU Wen-xian
ZHANG Wei-jun
Abstract：Objective To explore the effect of cardiac risk factors on the severity of coronary artery lesion in post menopausal women with coronary heart disease(CHD).Methods The study prospectively analyzed the post manopasual femal patients from 2012.9 to 2013.2 who were admitted for chest pain,chest tightness and got coronary angiography.According to the results of coronary angiography,the patients were divided into the CHD group (340 cases) and non-CHD group (113 cases).Results ①Single-variant analysis showed age,systolic blood pressure,diastolic blood pressure,pulse pressure,triglycerides,total cholesterol,low-density lipoprotein cholesterol (LDL-C) and risk factors had statistically significant difference between CHD group and non-CHD group [(63 ±8) old years vs (60 ± 9) old years,(149 ± 28) mm Hg(1 mm Hg=0.133 kPa) vs (128 ± 14) mm Hg,(88 ± 16) mm Hg vs (78 ±8) mm Hg,(61 ± 22)mm Hg vs (50 ± 12) mm Hg,(2.2 ± 1.2) mmol/L vs (1.8 ± 1.0) mmol/L,(4.6 ± 1.7) mmol/L vs (4.8 ± 1.0) mmol/L,(3.1 ± 0.8) mmol/L vs (2.1 ± 0.8) mmol/L; all P ＜ 0.05].②The multivariant logistic regression analysis showed systolic blood pressure,pulse pressure,triglyceride and LDL-C as an independent risk factors for women with CHD (P ＜ 0.05).Associated risk were as follows:triglycerides,LDL-C,pulse pressure,systolic blood pressure.③According to the degree of coronary artery disease,the coronary group patients were divided into single-vessel disease group (103 cases,30.3％),2-vessel disease group (114 cases,33.5％),3-vessel disease group (123 cases,36.2％).Age and LDL-C in coronary artery disease were significantly different among different groups[age:(61 ±8),(62 ±8),(64 ±8)old years; LDL-C:(2.9 ±0.7),(3.0 ±0.7),(3.2 ± 0.8) mmol/L; all P ＜ 0.05].Conclusion Cardiovascular risk factors plays an important role in postmenopausal women with CHD ; effectively controlling these risk factors is the key to prevention of CHD.
Keywords：Coronary heart diseaseWomenMenopauseRisk factors
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1681-1683 )