Difference on the expression of annexin A1 in unstable angina pectoris and acute myocardical infarction
AI Hui
ZHU Xiao-ling
WANG Cheng-gang
ZU Xiao-lin
WANG Chun-mei
Abstract：Objective To study the difference and significance on the expression of annexin A1 in unstable angina (UA) pectoris and acute myocardial infarction (AMI).Methods Ninety cases of hospitalized coronary herat disease(CHD) patients were divided into 2 groups.Fifty-four of them were in the UA group and 36 in the AMI group.Thirty cases were in control group.Before meal,the vein blood of the CHD patient group and the control group was drawn within 24 hours after the attack.The sera were centrifugalized and then preserved in-20 ℃ ice box for measurement.The quantity of annexin A1 was measured with double-antibody 125I radio-immunoassay.Results The expression difference of annexin A1 in three groups:control group (3.24 ± 0.16) μg/L,UA group (0.68 ± 0.15) μg/L,AMI (0.35 ± 0.18) μg/L.Expression of annexin A1 in UA and AMI group were higher than control group,the difference was statistically significant (all P ＜ 0.05).The expression of annexin A1 in patients with AMI was higher than UA group,the difference was statistically significant (P ＜ 0.05).Conclusion The decreased annexin A1 may be a risk factor of CHD and may be related to myocardial damage of AMI.
Keywords：Unstable anginaAcute myocardical infarctionAnnexin A1
Publication Date：2013-11-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 1531-1532 )