Cost-effect analysis of nifedipine, amlodipine and metoprolol in the treatment of essential hypertension
SONG Hao
MA Zhen-wu
CHEN Yong-xin
HUANG Su-pei
Abstract：Objective To study the cost-effect of nifedipine,amlodipine and metoprolol in the treatment of essential hypertension.Methods All 180 patients with essential hypertension were randomly divided into nifedipine group,amlodipine group and metoprolol group; each group had 60 cases.Nifedipine group was treated with nifedipine(30 mg per time,1 time per day),amlodipine group was treated with amlodipine (5 mg per time and 1 time per day) and metoprolol group was given metoprolol(50 mg per time,2 times per day).After 8 weeks,the clinical efficacy and cost-effect were compared.Results The clinical efficacy in amlodipine group was better than that in nifedipine group and metoprolol group[95.0％ (57/60) vs 85.0％ (51/60),78.3％ (47/60),P ＜0.05] ; the cost-effectiveness among nifedipine group,amlodipine group and metoprolol group were 3.57,2.32 and 1.54.The incremental cost among nifedipine group,amlodipine group were 18.22 and 5.94.Conclusion Amlodipine has the best cost-effect in the three drugs for treatment of older essential hypertension.
Keywords：Essential hypertension,elderlyNifedipineAmlodipineMetoprololCost-effect
Publication Date：2013-10-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 1386-1387 )