Analysis of children with leukaemia after using antibacterial drugs
LI Hong-jian
ZHANG Qin-cang
LIU Wen-li
YU Lu-hai
ZHONG Hua
Abstract：Objective To analyze the clinical features of nosocomial infection and the usage of antibiotics of pediatric patients with leukemia.Methods Nosocomial infection predisposing factors were analyzed retrospectively in 200 pediatric leukemia patients who were admitted to hospital during 2011.Results The hospital acquired infection rate of pediatric patients with leukemia was 72.5％ (145/200).The infection rates of pediatric patients with leukemia were 80.0％ and 83.6％ (61/73) respectively when the peripheral WBC counts were less than 1 × 109/L and the patients'duration of hospital stay were more than 30 d.The mainly pathogens were Gram-negative aerobic bacteria.The most common infective sites respectively were:Upper respiratory tract with infection rate of 74.2％.Three generation cephalosporins were most commonly used,the frequency of use was 29.9％.Infection in children with leukemia was related with the level of their peripheral blood neutrophils decreasing and the stay time of children inthe hospital (P ＜0.05 or P ＜0.01).Conclusions Pediatric patients with leukemia have high nosocomial infection rate.It reveals that this infection in pediatric leukemia patients is related to the patients' duration of hospital stay,peripheral WBC counts.The standardzed antibiotic usage can help to reduce the nosocomial infection occurrence.
Keywords：LeukaemiaInpatients childrenAntibiotics
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 1257-1258 )