Resistance analysis of 164 strains of meticillin-resistant staphylococcus aureus in diabetic foot fangrene
WU Shi-bai
GUAN Xiao-hong
WANG Lu-ning
WANG Liang-chen
HE Xiao-feng
WU Di
Abstract：Objective To study the current situation of infection onset caused by methicillin-resistant staphylococcus aureus (MRSA) in diabetic foot gangrene,benefit clinical to select antibiotic for use reasonably,and prevent MRSA epidemic-outbreak.Approach the evidence for clinical prevention and cure.Methods The research was done to detect MRSA in 411 samples from patients suffering from diabetic foot gangrene in hospital which was infected by staphylococcus aureus from January 2008 to December 2011.Bacterial isolates were identified by API system,the susceptibility of antibiotics was performed by Kirby-Bauer method,and Kirby-Bauer method of cefoxitin was used to select meticillin-resistant Staphylococcus aureus MRSA.Results Of 411 strains of isolated staphylococcus aureus,164 strains were MRSA and 247 strains were meticillin-sensitive Staphylococcus aureus (MSSA).Except for penicillin,erythromycin and clindamycin,MSSA were sensitive to the other antibiotics.While MRSA were only sensitive to vancomycin,linezolid,teicoplanin,nitrofurantoin,chloramphenicol and trimetthoprim/sulfamethoxazolen,and were resistant to all other antibiotics.No strain which was resistant to vancomycin and linezolid was isolated.Conclusions MRSA is multidrug resistant.the drug resistances of MRSA should be monitored closely in diabetic foot gangrene to effectively prevent and control its infection.
Keywords：Staphyloccocus aureus rosenbachMethicillin-resistant staphylococcus aureusInfectionDrug resistance
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1241-1243 )