Azithromycin with budesonide/formoterol turbuhaler in the treatment of bronchial asthma
HAO Lu
CUI Li-ying
Abstract：Objective To explore the clinical effect of azithromycin combined with budesonide/formoterol turbuhaler for asthmatic patients.Methods Totally 50 patients were randomly divided into budesonide/formoterol turbuhaler for inhalation group (single drug group,n =25) and azithromycin and budesonide/formoterol turbuhaler for inhalation group (combined group,n =25).The curative effect of tow groups and lung function change and adverse reaction were observed.Results After treatment for 1 week and 3 months,the scores of asthmatic symtoms in single drug group and combined group were less than those before treatment [the symtoms of day time in single drug group:(0.96 ± 0.78),(0.50 ± 0.40) scores vs (3.76 ± 1.16) scores; the symtoms of night time in single drug group:(0.76 ± 0.38),(0.22 ± 0.02) scores vs (3.32 ± 0.18) scores ; the symtoms of day time in combined group:(0.56 ± 0.51),(0.28 ± 0.08) scores vs (4.04 ± 0.84) scores; the symtoms of night time in combined group:(0.52-0.25),(0.04 ± 0.03)scores vs (3.44 ± 0.20) scores],and the FEV1/FVC were higher than those before treatment [single drug group:(65.5 ± 2.0) ％,(73.8 ± 1.4) ％ vs (58.5 ± 1.8) ％ ; combined group:(68.7 ±1.3) ％,(82.1 ± 0.8) ％ vs (58.2 ± 1.8) ％],and there were significant differences (all P ＜ 0.05).Mter treatment for 1 week and 3 months,the scores of asthmatic symtoms in combined group were less than those in single drug group,and the FEV1/FVC were higher than those in single drug group (all P ＜ 0.05).Two groups in treatment period did not have serious adversr reactions.Conclusion Use of azithromycin and budesonide/formoterol turbuhaler in bronchial asthma has good curative effect.
Keywords：AsthmaAzithromycinBudesonide/formoterol turbuhaler
Publication Date：2013-09-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1231-1233 )