Clinical effect of creatine phosphate sodium in the treatment of chronic heart failure
PENG Wen
Abstract：Objective To discuss the clinical effect of creatine phosphate sodium in the treatment of chronic heart failure.Methods One hundred and eighty cases with chronic heart failure were randomly divided into treatment group (90 cases) and the control group (90 cases).Treatment group was given normal heart failure drugs combined with creatine phosphate sodium,and control group was given normal heart failure drugs.The total effect rate,left ventricular ejection fraction (LVEF),left ventricular end-systolic diameter (LVESD),left ventricular end diastolic diameter(LVEDD),brain natriuretic peptide (BNP),creatine kinase-MB (CK-MB) and Minnesota life quality score after treatment of two groups were observed and compared.Results The total effect rate of treatment group was 82.2％,and 74.4％ in control group,there was significant difference (P ＜ 0.05).After treatment,LVESD,LVEDD,BNP,CK-MB of treatment group [(46 ±6)mm,(56 ±5)mm,(320 ± 107) ng/L,(4.2 ±1.2) U/L] significantly decreased compared with the control group [(50 ±7)mm,(62 ± 6)am,(392 ± 121)ng/L,(9.1 ± 1.5)U/L] (P＜0.05),LVEF [treatment group:(58 ±5)％ ; control group:(47 ±6)％] increased significantly (P ＜ 0.05).Minnesota life quality score of treatment group [(35 ± 10)scores] was lower than that of control group [(40 ± 13)scores] (P ＜ 0.05).Conclusions Creatine phosphate sodium can improve the cardiac function of chronic heart failure patients,improve the quality of life and effectively optimize the conventional treatment of chronic heart failure.
Keywords：Chronic heart failureCreatine phosphate sodiumConventional treatment
Publication Date：2013-09-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 1209-1210 )