The relation between serum homocysteine levels and age in patients of high blood pressure combined with anxiety state
LIU Mei-yan
JIANG Rong-huan
GUO Cheng-jun
Abstract：Objective To study the relation between serum homocysteine levels and age in patients of high blood pressure combined with anxiety state.Methods Totally 164 patients with primary hypertension were assessed in health questionnaire depression scale (PHQ-9) and generalized anxiety scale (GAD-7).According to merge anxiety,all patients were divided into no anxiety group (28 cases),mild-to-moderate anxiety group (81 cases) and severe anxiety group (55 cases).GAD-7 levels of patients were analyzed.Homocysteine,low density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol (HDL-C),high sensitive C-reactive protein and fibrinogen level of patients were detected; the differences among the three groups and the anxiety degree of correlation in combination with high blood pressure were compared.Results Mean age of no anxiety group,mild-to-moderate anxiety group and severe anxiety group was (58.1 ± 2.4),(58.2 ± 2.0),(60.6 ± 2.3) years respectively.Hcy was (12.8 ± 0.8),(16.4 ± 0.7),(17.4 ± 1.1) μmol/L respectively; there were significant differences on the age and Hcy among three groups (P ＜ 0.05).Analysis showed that GAD-7 score was associated with PHQ-9 scores ; correlation coefficient was 0.581 (P ＜ 0.01).Multiple regression analysis showed that PHQ-9,Hcy and age were the important factors that affected hypertension combined anxiety state score.Conclusion Hcy levels and age factors are associated with degree of hypertension combined anxiety state.
Keywords：HypertensionAgeAnxietyHomocysteine
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1055-1057 )