Analysis of the role of statin drugs in the treatment of atrial fibrillation
PAN Cong-ming
CHANG Qing-mei
HAO Shi-guo
LIU Shu-zhen
Abstract:Objective To detect the role of statin drugs in the treatment of atrial fibrillation.Methods Totally 86 cases with atrial fibrillation were collected between January 2008 and January 2011.The patients were randomly divided into two groups.After being given in vitro synchronous dc after cardioerter,both groups had amiodarone 200 mg (200 mg/piece) with 3 times a day,200 mg with 2 times a day after one week,and 200 mg once a day for a long term.Statin group also had simvastatin 20 mg (20 mg/piece) every night.All patients were given warfarin sodium fomal anticoagulant therapy before and after cardioerter.Total treatment was for 6 months.Results The statin group showed sinus rhythm in 38 cases (88.4%) ; the control group showed sinus rhythm in 29 cases (67.4%).The proportion of sinus rhythm in simvastatin group was significantly higher than that in the control group (88.4% vs 67.4%,P<0.05).Conclusion Statins can prevent recurrence of atrial fibrillation.
Keywords:Atrial fibrillationStatins drugSimvastatin
Publication Date:2013-01-01
Online Publishing Date:2026-09-14(First online date of this platform, not the publication date of the document)
Pages:2( 1043-1044 )
