Relationship between carotid atherosclerosis and plasma homocysteine level in patients with acute cerebral infarction
Abstract：Objective To investigate the relation between the serum homocysteine level in patients with acute cerebral infarction and carotid artery atherosclerosis.Methods In 103 patients with initial acute cerebral infarction and 46 healthy persons,carotid intima-medial wall thickness(IMT) was determined with colored doppler ultrasound; serum homocysteine level was determined with immunoturbidimetry.Results The serum homocysteine level in the patient group was significantly higher than that in control group[(18.21 ±0.51) μmol/L vs (12.32 ±0.16) μmol/L,P ＜ 0.01].The serum homocysteine level in the patients with carotid artery intima media thickness oratheromatous plaque was significantly higher than that in the patients without atheromatous plaque [(18.37 ±0.24),(20.16 ±0.58) μmol/L vs (13.25 ±0.13) μmol/L,P＜0.05].The serum homocysteine level of patients with atheromatous plaque was significantly higher than that of patients with carotid artery intima media thickness(P ＜0.05) ; the serum homocysteine level was positively correlated with intimal-medial wall thickness (r =0.68,P ＜0.01).Conclusion The serum homocysteine level is significantly correlated with the degree of atherosclerosis of patients with acute cerebral infarction.
Keywords：HomocysteineCerebral infarctionacuteCarotid artery atherosclerosis
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 917-918 )